Events
CEMINAR
The most important community-oriented activity we sponsor is CEMINAR, formerly MicroMorning, a monthly seminar series where students and postdocs in the CEMI program present their work. Usually 2 individuals present 20-25 min talks (+ 5 min questions) to fill the hour, but on rare occasions we invite an outside speaker. CEMINAR is primarily designed to provide CEMI students and postdocs with an opportunity to practice giving a formal talk to a friendly Caltech audience. Numerous collaborations have been sparked between labs at Caltech thanks to creative connections made during these seminars. View past CEMINARS
CEMINAR
CEMINAR is on the second Wednesday of every month.
UPCOMING
Wednesday, November 13, 2024, 4:00 pm
4:00-5:00pm Chen 130
5:00-5:30pm Socializing (snacks and drinks will be provided)
"Towards declarative bioengineering"
Zach Martinez
Murray Lab
Due to the deluge of data humanity has amassed, deep-learning has been rapidly adopted by many fields. Contemporary deep-learning models are often unwieldy, especially for scientists with limited machine learning backgrounds. TRILL (TRaining and Inference using the Language of Life) is a platform for creative protein design and analysis. Leveraging state-of-the-art models, TRILL allows researchers to generate novel proteins, predict 3-D structures, perform molecular docking/dynamics simulations and more. Whether using Google Colab with one GPU, a supercomputer with hundreds or a laptop with none, TRILL bridges the gap between complex models and their practical application in biology and bioengineering.
"Multiplexed ultrasound imaging of gene expression"
Nivin Nasri
Shapiro Lab
Acoustic reporter genes (ARGs) have enabled imaging of gene expression with ultrasound, which provides high-resolution access to deep, optically opaque living tissues. However, unlike their fluorescent counterparts, ARGs have so far been limited to a single “color,” preventing multiplexed imaging of cellular states or populations. We use rational protein design and directed evolution to develop two novel ARGs that can be distinguished from each other based on their acoustic pressure responses, enabling “two-color” ultrasound imaging of gene expression. We demonstrate the utility of multiplexed ARGs for delineating bacterial cell species and cell states in vitro, and then apply them towards imaging distinct subpopulations of probiotics in the mouse gastrointestinal tract and in tumor-colonizing bacterial agents in vivo.
Social Events
In addition to CEMINAR, CEMI sponsors social events during the academic year:
Fall Poster Sessions: All CEMI labs present one or more posters on their lab’s research. This helps incoming/current students and postdocs remain up-to-date on that latest research projects going on across the campus. One attractive feature of Caltech is that students admitted in any graduate program are welcome to rotate in any lab (as long as the lab is taking students), so this poster session can open up new interests and areas for exploration. It also can spawn new collaborations between labs.
Spring Lectures and Evening Gala: To celebrate the start of the calendar year, we invite a keynote speaker from outside Caltech to give a seminar, plus a few shorter talks by assistant professors or postdocs at Caltech and other local universities. These “Spring Lectures” are open to anyone interested. As a companion event, we hold a formal gathering for a limited number of CEMI sponsors, faculty, and students and postdocs currently being supported by CEMI grants. The evening’s entertainment is organized by a different CEMI lab each year, and the evening culminates with a presentation of the “CEMI Oscars” (we are close to Hollywood, after all…), roasting CEMI members for notable achievements in the past year, all in good fun. View past lectures
Spring Happy Hour: In recognition of the fact that sometimes the most inspired ideas come when we least expect them, we promote casual conversation between all members of the CEMI community supplemented with drinks and food at the start of the spring term (no posters required!).
CEMI Spring Celebration of Science: This hour-long science program featured short lightning talks from CEMI graduate students and postdocs followed by time to talk with the speakers and socialize with our CEMI colleagues. The inaugural event was held on May 12, 2021.
Workshops
CEMI occasionally supports training courses at Caltech that provide members of the CEMI community with an opportunity for intensive training in a particular area. Any member of the CEMI community is welcome to suggest a topic for a workshop. Please contact the CEMI administrator if you have an idea. View past workshops
